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doi: 10.2450/2017.0366-16, Summary Keywords CD36, CD47, ICAM-4, PIEZO1, RBC aging, red blood cell Citation Almadhaani KY, Altaie AM and Hamoudi R (2026) Molecular profiles of red blood cells across geographic, pathological, and age-related perspectives: translational insights

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Our roGFP2 measurements confirm (i) that dynamic roGFP2 sensing (or the physiological glutathionylation/deglutathionylation of regular surface-exposed cysteinyl residues) requires a glutaredoxin activity, and (ii) that glutathionylated proteins or metabolites should be very transient redox species when GSH and glutaredoxins are present (unless they are stabilized by a kinetic uncoupling mechanism) 5,32,34,35,61,62,63,64